Symbol
Name
ID

Ace2
angiotensin converting enzyme 2
MGI:1917258

Phenotype annotations related to immune system

Darker colors indicate more annotations

Mouse Phenotypes

heart inflammation

increased susceptibility to induced colitis

intestinal inflammation

abnormal thymus morphology

enlarged thymus

enlarged spleen

increased neutrophil cell number

abnormal spleen morphology

abnormal circulating cytokine level

increased circulating interferon-gamma level

increased circulating interleukin-9 level

abnormal cytokine level

increased incidence of corneal inflammation

lung inflammation

interstitial pneumonia

increased susceptibility to bacterial infection

increased susceptibility to bacterial infection induced morbidity/mortality

increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality

decreased susceptibility to Coronaviridae infection

increased susceptibility to Coronaviridae infection

increased susceptibility to Orthomyxoviridae infection

Availability

Mouse Genotype

Ace2^{em1(ACE2)Yowa}/Ace2^{em1(ACE2)Yowa}

Ace2^{em1(IMPC)Ccpcz}/Ace2^{em1(IMPC)Ccpcz}

Ace2^tm1Cof/Ace2^tm1Cof

Ace2^tm1Lex/Ace2^tm1Lex

Ace2^tm1Pngr/Ace2^tm1Pngr

Ace2^{em1(IMPC)Ccpcz}/Y

Ace2^em1Cya/Y

Ace2^em#Yngh/Y

Ace2^tm1Pngr/Y

Ace2^{tm1a(KOMP)Wtsi}/Ace2^{tm1a(KOMP)Wtsi}
Tg(FOXJ1-cre)F26Htzm/0 (conditional)

Ace2^{tm1a(KOMP)Wtsi}/Y
Tg(FOXJ1-cre)F26Htzm/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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